1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1072R
    Phenothrin (Standard)
    Inhibitor
    Phenothrin (Standard) is the analytical standard of Phenothrin. This product is intended for research and analytical applications.
    Phenothrin (Standard)
  • HY-149985
    Antitrypanosomal agent 12
    Inhibitor
    Antitrypanosomal agent 12 is a C20-phenylthiourea with trypanocidal and cytotoxic activities. Antitrypanosomal agent 12 shows antitrypanosomal activity with 50% growth inhibition (GI50) values of 0.22 μM. Antitrypanosomal agent 12 induces faster cell swelling in bloodstream-form trypanosomes than Salinomycin (HY-15597).
    Antitrypanosomal agent 12
  • HY-N6587
    Betulinic acid methyl ester
    Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity.
    Betulinic acid methyl ester
  • HY-17595S
    Mebendazole-d3
    Mebendazole-d3 is the deuterium labeled Mebendazole.
    Mebendazole-d<sub>3</sub>
  • HY-120607
    Chevalone C
    Inhibitor
    Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines.
    Chevalone C
  • HY-150506
    SPR7
    Inhibitor
    SPR7 (compound 7) is a potent and selective rhodesain inhibitor, with a Ki of 0.51 nM. SPR7 shows antiparasitic activity against T. b. brucei, with an EC50 of 1.65 μM.
    SPR7
  • HY-144700
    Antileishmanial agent-3
    Antileishmanial agent-3 (Compound 13) is a promising growth inhibitor of Leishmania major.
    Antileishmanial agent-3
  • HY-N11100
    Geranin A
    Inhibitor
    Geranin A is an A-type proanthocyanidin. Geranin A can be isolated from the antiprotozoal extract of Geranium niveum.
    Geranin A
  • HY-148423
    Picarbutrazox
    Inhibitor
    Picarbutrazox is a potent pesticide and fungicide. Picarbutrazox can be used for corn and soybean to control Pythium and Phytophthora. Picarbutrazox can be used in agricultural production and control.
    Picarbutrazox
  • HY-123915
    Antimalarial agent 20
    Inhibitor
    Antimalarial agent 20 (Compound 49c) is an antimalarial agent with an IC50 of 0.6 nM against P. falciparum NF54 parasite strain in the NF54 albumax assay.
    Antimalarial agent 20
  • HY-146045
    Antiparasitic agent-7
    Inhibitor
    Antiparasitic agent-7 (compound 5d) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.85 μM. Antiparasitic agent-7 also has certain cytotoxicity against HepG2 (CC50 = 10.61 μM).
    Antiparasitic agent-7
  • HY-116448S
    Metaflumizone-d4
    Inhibitor
    Metaflumizone-d4 is deuterium labeled Metaflumizone. Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker[1].
    Metaflumizone-d<sub>4</sub>
  • HY-116448R
    Metaflumizone (Standard)
    Inhibitor
    Metaflumizone (Standard) is the analytical standard of Metaflumizone. This product is intended for research and analytical applications. Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker.
    Metaflumizone (Standard)
  • HY-B1282AR
    Sulfaquinoxaline (sodium salt) (Standard)
    Inhibitor
    3β-Ursodeoxycholic acid (Standard) is the analytical standard of 3β-Ursodeoxycholic acid. This product is intended for research and analytical applications. 3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid shows good tolerance and well intestinal absorption by oral adminstation. 3β-Ursodeoxycholic acid can be isomerized by intestinal and hepatic enzymes to yield UDCA.
    Sulfaquinoxaline (sodium salt) (Standard)
  • HY-168732
    MCG-02
    Inhibitor
    MCG-02 is the inhibitor for cruzain (CRZ) and cathepsin L-like protease (CATL), that inhibits the CRZ in Trypanosoma cruzi and CATL in Trypanosoma brucei with the IC50 0.2 μM and 0.02 μM.
    MCG-02
  • HY-148216
    HBPC–GSH
    Inhibitor
    HBPC-GSH is a glyoxalase (Glo) inhibitor (cGloI IC50=0.6 μM; cGloII IC50=1.6 μM), a glutathione derivative. HBPC-GSH can be used in antimalarial research.
    HBPC–GSH
  • HY-N8476
    Sahandol
    Inhibitor
    Sahandol is a diterpene, that can be isolated from Salvia sahendica. Sahandol shows antiplasmodial, antitrypanosomal, and cytotoxic activities.
    Sahandol
  • HY-14749
    Pyronaridine
    Inhibitor
    Pyronaridine is an orally active Mannich base anti-malarial agent. Pyronaridine is active against P. falciparum and Echinococcus granulosus infection.
    Pyronaridine
  • HY-138074
    Milbemycin A4 oxime
    Milbemycin A4 oxime (5-Ketomilbemycin A4 oxime; 5-Oxomilbemycin A4 5-oxime) is a derivative of Milbemycin A4 (HY-126906) and a component of Milbemycin oxime (HY-B0778), both of which have insecticidal and nematicidal activities. Milbemycin A4 oxime (0.05 mg/kg) reduces the number of microfilariae in naturally infected dogs with D. immitis and inhibits the growth of clinical isolates of Candida glabrata (MIC80=16-32 μg/mL). Milbemycin A4 oxime (2.5 μg/mL) blocks the efflux of Fluconazole (HY-B0101) from clinical isolates of Candida glabrata. Milbemycin A4 oxime enhances doxorubicin-induced cell growth inhibition and increases the intracellular accumulation of doxorubicin and P-glycoprotein substrate Rhodamine 123 (HY-D0816) in doxorubicin-resistant but not sensitive MCF-7 breast cancer cells in a concentration-dependent manner.
    Milbemycin A4 oxime
  • HY-115249R
    Metronidazole acetic acid (Standard)
    Inhibitor
    Metronidazole acetic acid (Standard) is the analytical standard of Metronidazole acetic acid. This product is intended for research and analytical applications. Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa.
    Metronidazole acetic acid (Standard)

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